منابع مشابه
Modulation of Conjunctival Goblet Cell Function by Inflammatory Cytokines
Ocular surface inflammation associated with Sjögren's syndrome is characterized by a loss of secretory function and alteration in numbers of mucin secreting goblet cells. Such changes are a prominent feature of ocular surface inflammatory diseases and are attributed to inflammation; however, the exact effect of the inflammatory cytokines on conjunctival goblet cell function remains largely unkn...
متن کاملGoblet cell density and vascularization during conjunctival transdifferentiation.
After debridement of the entire corneal epithelium with n-heptanol, two groups of rabbit corneas were segregated according to the extent of corneal neovascularization. Using a new topographic goblet-cell counting method and routine histology, the authors have reexamined the process of conjunctival transdifferentiation and compared the changes of goblet-cell density and morphology between nonvas...
متن کاملImmunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins. Loss of these cells is associated with several chronic inflammatory disorders of the mucosa. Although demonstrated to transfer antigens from the luminal surface to stromal cells in the intestinal mucosa, it is not known if g...
متن کاملEffect of topical rebamipide on human conjunctival goblet cells.
to be associatedwith HPV 16. Higher-weight cytokeratins are encountered in the epidermis as opposed to mucous membranes.2,3 The 2 major differential diagnoses were sebaceous and mucoepidermoid carcinomas.4 Sebaceous carcinomawasexcludedbyoil redOcytoplasmicnegativityand immunohistochemical stains that demonstrated negativity for both adipophilin (except for faint focal positivity in necrotic zo...
متن کاملIsolation and characterization of cultured human conjunctival goblet cells.
PURPOSE To isolate and characterize goblet cells from normal human conjunctival tissue to determine whether epidermal growth factor (EGF) receptors are present and whether EGF can influence goblet cell proliferation. METHODS Goblet cells were isolated from explant cultures established from normal conjunctival tissue harvested from patients during periocular surgery. The cells were grown in RP...
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ژورنال
عنوان ژورنال: Eye & Contact Lens: Science & Clinical Practice
سال: 2016
ISSN: 1542-2321
DOI: 10.1097/icl.0000000000000158